With the help of our CURItive™ platform, we can search for new promoter candidates to increase the selectivity of oncolytic viruses in certain diseases.
In addition, by using the CURItiveTM platform, we were able to develop our own scoring system using multiple parameters including alignment sequences in target genes. this also allows us to reduce the probability of off-target effects.
(a) Curigin’s database
(b) CURItiveTM algorithm indicates the genes that are over specifically overexpressed in a specific disease
(c) Our database can detect promoters that are crucial for certain diseases
(d) Align 2 genes for small hairpin RNAs
(e) During gene cleavage: NO passenger genes, NO off targets effects and side effects